MANAGEMENT OF ARTERIAL COMPLICATIONS AFTER LIVING DONOR LIVER TRANSPLANTATION

Document Type : Original Article

Authors

Department of General Surgery, Faculty of Medicine - Ain Shams University

Abstract

Background: Liver transplantation is perceived as the only curative treatment for patients with end-stage liver disease. Arterial complications are one of the most serious complications after living donor liver transplantation (LDLT).
Aim of the work: To assess the different modalities of management and outcome of early and late arterial complications and to analyze the risk factors of such complications after living donor liver transplantaiton. Patients and Methods: This is a retrospective study in which 293 LDLT operations were done between 2008 and May 2017 at Ain Shams center for organ transplantation (ASCOT). After approval of Ethics committee and the research council, Ain shams university
school of medicine, we did this retrospective cohort study that analyzed the incidence, risk factors, management and outcome of HA complications in adults and pediatrics recipients in the period from 2008 to May 2017, where patients were observed from POD 1 until the end 2017 or until death of patients. Results: In our study early arterial complications are more higher and more serious than late arterial complications. Mortality rate in patients with early complications exceeds 50%.In late complications it was 20%. Conclusion: Urgent surgical management is life saving in cases of early hepatic artery thrombosis (HAT). Arterial reconstruction is technically difficult. LD retransplant has been performed in a very small number worldwide. Emergency living donor retransplantation is life saving in cases of early (HAT). Arterial reconstruction using left gastric artery and splenic artery is feasible in LD retransplant and arterial reconstruction after HAT. Early diagnosis and surgical or radiological intervention is the corner stone to save the recipient.

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