MYOCARDIAL PROTECTION USING DEL NIDO CARDIOPLEGIA SOLUTION COMPARED TO ON-PUMP BEATING MITRAL VALVE REPLACEMENT IN CHRONIC SEVERE MITRAL INCOMPETENCE

Document Type : Original Article

Authors

1 Cardiac surgery, National Heart Institute, Cairo, EGYPT.

2 cardiology department, National Heart Institute, Cairo, EGYPT.

Abstract

Introduction: Del Nido cardioplegia is widely used nowadays in adult cardiac surgery. Beating heart valvular surgery is gaining more popularity and used by many cardiac centers nowadays. Both is used currently in cases of chronic mitral valve incompetence with left ventricle impairment.
Aim of the work: To compare the outcome of Del Nido cardioplegia and beating surgery in cases of mitral valve replacement and left ventricular impairement.
Patients and methods: This is a clinically randomized trial conducted in National Heart Institute during the period from June 2020 till December 2021. It contains sixty patients with chronic severe mitral incompetence indicated for isolated mitral valve replacement using two different modalities of myocardial protection. Patients were divided into two groups: group (A) containing 30 patients receiving Del Nido (ND) cardioplegia , and group (B) containing also 30 patients underwent mitral valve replacement through beating heart surgery.
Results: Del Nido cardioplegia has a shorter surgical time than beating heart surgery, yet it has the same ventilation time , intensive care unit stay and need for inotropic support during weaning from bypass. Beating heart surgery had a lower level of post operative troponin release.
Conclusion: Del Nido cardioplegia is a safe and effective method of myocardial protection during mitral valve replacement with left ventricular impairement.

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Ain Shams Medical Journal
Volume 73, Issue 1
March 2022
Pages 115-122

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