Evaluation of role of combined PET/CT Scanning in Identification of Osseous and Marrow Metastatic Deposits

Sharara, Sherine M.; Abdelfadil, Mostafa Abdelwahab Hussein; Elnaggar, Heba

doi:10.21608/asmj.2023.233992.1164

Evaluation of role of combined PET/CT Scanning in Identification of Osseous and Marrow Metastatic Deposits

Document Type : Original Article

Authors

¹ Assistant Professor of Diagnostic and Interventional Radiology - Faculty of Medicine - Ain Shams University, Cairo, Egypt.

² Diagnostic and Interventional Radiology Department - Faculty of Medicine - Ain Shams University, Cairo, Egypt.

³ Lecturer of Diagnostic and Interventional Radiology - Faculty of Medicine - Ain Shams University, Cairo, Egypt.

10.21608/asmj.2023.233992.1164

Abstract

Background: To improve a patient's long-term survival and reduce potential hematological, neurological, and orthopedic challenges, early cancer identification is critical. Osseous and marrow deposits are frequently seen as significant cancer consequences that can cause excruciating pain and have a bad prognosis.
Objectives: The study's objective was to show how combined 18F-FDG PET/CT is superior to standalone CT in detecting osseous and marrow deposits in cancer patients.
Patients and Methods: There were 75 participants in the trial, and 18F-PET/CT scans were carried out. Retrograde lesion-based analysis was carried out. The negative predictive value (NPV), positive predictive value (PPV), sensitivity, and specificity of each of these modalities were assessed as part of the statistical study. Whenever feasible, a biopsy of the underlying neoplastic lesion, pattern of dissemination, and follow-up were used to confirm a final diagnosis of metastasis.
Results: The detection of osseous and bone marrow metastatic deposits which are not visible on traditional CT studies is made possible by combined PET-CT examination, an extraordinarily sensitive imaging technique.
Conclusion: The identification of osseous and bone marrow metastases was reported to be substantially more sensitive and specific with combined 18-F FDG PET/CT than with standalone CT. In order to start a treatment regimen and improve the overall prognosis and result of the illness process, it adds a major value that can detect lesions.

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