Background/Aims: To study the effectiveness of intravitreal ranibizumab injection (IVR) in the treatment of acute central serous chorioretinopathy (CSCR). Methods: A Prospective, randomized, single-center, parallel-arm, controlled trial study the involved patients had symptoms of CSCR with less than 3 months duration. Patients (n = 50/ divided into 2 groups) the anti-VEGF group with 30 patients injected with intravitreal Ranibizumab(IVR) (0.5 mg/0.05 ml) and an observation group where 20 patients were observed, each group were followed for 4 months. Best-corrected visual acuity (BCVA), and central macular thickness (CMT) were assessed by Ocular coherent tomography (OCT) for first baseline and then at regular follow-ups. Results: All patients had improved and increased BCVA, with decreased CMT, and resolution of the subretinal fluid. The mean CMT in IVR and observation groups was 117.33±46.2μm and 196.70±36.9μm, respectively (P = 0.670) The mean BCVA and mean CMT improved significantly in both groups at 4 weeks , but the changes were not significantly different between both groups at 4months. Conclusions: both IVR and observation for acute CSCR improved the resolution of subretinal fluid. BCVA and CMT did not differ at 4 months, between IVR and observation groups. So we advised a Further studies are required to determine the long-term benefits of IVR.
Abdulhadi, Y., & Bukhatwa, S. (2024). EFFECTIVNESS OF INTRAVITREAL RANIBIZUMAB (LUCENTIS) IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY TREATMENT. Ain Shams Medical Journal, 75(1), 231-238. doi: 10.21608/asmj.2024.353821
MLA
Yasmena M Abdulhadi; Samar A Bukhatwa. "EFFECTIVNESS OF INTRAVITREAL RANIBIZUMAB (LUCENTIS) IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY TREATMENT", Ain Shams Medical Journal, 75, 1, 2024, 231-238. doi: 10.21608/asmj.2024.353821
HARVARD
Abdulhadi, Y., Bukhatwa, S. (2024). 'EFFECTIVNESS OF INTRAVITREAL RANIBIZUMAB (LUCENTIS) IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY TREATMENT', Ain Shams Medical Journal, 75(1), pp. 231-238. doi: 10.21608/asmj.2024.353821
VANCOUVER
Abdulhadi, Y., Bukhatwa, S. EFFECTIVNESS OF INTRAVITREAL RANIBIZUMAB (LUCENTIS) IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY TREATMENT. Ain Shams Medical Journal, 2024; 75(1): 231-238. doi: 10.21608/asmj.2024.353821