Assessment of Heart Failure with Preserved Systolic Function Using Two-dimension Speckle Tracking Echocardiography

Document Type : Original Article

Authors

Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Abstract

Background: Heart failure (HF) is characterised as a multifaceted clinical condition linked to either a functional or structural
reduction in ventricular blood filling or ejection capability. In numerous countries, this condition is typically the most frequently
diagnosed in individuals aged 65 or above.
Aim: To assess the importance of speckle tracking in assessing patients with heart failure who have a preserved ejection
fraction.
Methods: This prospective cohort study, comprising 200 patients aged 18-70 years, including both sexes with heart failure
and a preserved ejection fraction, employed transthoracic speckle tracking echocardiography (STE). Echocardiography,
specifically transthoracic echocardiography and stress echocardiography was evaluated for all patients.
Results: The mean value of left ventricular (LV) end-diastolic dimension was 47.76±8.3 mm, LV end-systolic dimension
was 24.07 ±5.9 mm and LV ejection fraction was 59.28 ±7.18 %. Regarding speckle tracking parameters, the mean value of
global strain was -16.4 ±1.16 % and global strain rate was 1.2±0.46). HF with preserved ejection fraction score (HFpEF) was
low in 132 (66%) patients, Intermediate in 46 (23%) patients and high in 22 (11%) patients with median 1 (0-3). Global strain
and global strain rate (%) can significantly diagnosis of HF with preserved ejection fraction respectively at cut-off >-18.5 and
≤1.79) with 96.50% and 89.00% sensitivity, 51.50% and 60.50% specificity.
Conclusions: Speckle tracking can be a useful tool for the diagnosis of HF with HFpEF.

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