Role of MRI in Assessment of the Response Post High-Intensity Focused Ultrasound (HIFU) Treatment in Uterine Fibroids

Document Type : Original Article

Authors

1 Ain Shams university

2 Department of Diagnostic & Intervention Radiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

3 Diagnostic and Intervention Radiology department, National Hepatology and Tropical Medicine Research Institute.

4 Department of Radio-diagnosis, Faculty of Medicine, Ain Shams University

10.21608/asmj.2025.361009.1393

Abstract

Background: Fibroids are the most common benign uterine tumors in women of child-bearing period. They cause an array
of symptoms as dysmenorrhea, menorrhagia, menometrorrhagia, and even discomfort in the lower abdomen and infertility.
Sometimes, these fibroids exert pressure on neighboring organs, leading to disruptions in urination and defecation.
Aim of the Work: To evaluate the role of MRI in assessment of uterine fibroids response post HIFU treatment
Patients and Methods: In this prospective study, thirty adult females with uterine fibroid diagnosed by contrast-enhanced
MRI underwent HIFU ablation therapy. The clinical and laboratory outcomes were assessed in correlation with the MRI
findings as regards the non-perfused (NPV) percent and volume.
Results: The menstruation and pain score were notably reduced. There was substantial reduction in fibroid volume post-
treatment. Reduction in NPV correlated strongly with symptom improvement. The NPV measurement was central to evaluating
the procedure's success.
Conclusion: HIFU is a non-invasive, uterus-preserving treatment. The NPV can be used as a crucial metric for assessing
treatment outcomes and guiding clinical decisions and hence, serving as a pivotal marker of treatment success.

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