Evaluation of Peripheral Tissue Oxygenation in Preterm Neonates with Normal Transition

Abd El Fatah, Hania Ibrahim; Elmesiry, Asmaa Mahmoud; El Amrousy, Doaa Mohamed; Awny, Mostafa Mohamed

doi:10.21608/asmj.2025.346371.1354

Evaluation of Peripheral Tissue Oxygenation in Preterm Neonates with Normal Transition

Document Type : Original Article

Authors

¹ Assistant Lecturer of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt.

² Pediatrics Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

³ Pediatrics Department, Faculty of Medicine, Tanta University, Tanta, Egypt

10.21608/asmj.2025.346371.1354

Abstract

Background: Any birth that occurred before the full 37 weeks of pregnancy was considered preterm. Prematurity affected normal transitions which might impact tissue perfusion and oxygenation.
Aim: To evaluate mixed venous oxygen saturation (ScVO2) of inferior vena cava as an indicator of peripheral tissue oxygenation in preterm neonates and to correlate findings with hemodynamics reported by electrical cardiometry in preterm neonates during transition.
Methods: This observational prospective cohort study included 31 preterm neonates less than 34 weeks gestation admitted to a special care unit, neonatal intensive care unit, Tanta University Hospital; only for feeding and growth monitoring. Research investigations on postnatal days 4 and 10 included blood gas obtained from a centrally inserted umbilical venous catheter to measure central venous oxygen saturation from the Inferior Vena Cava (ScVO2). A Bedside Electrical cardiometry study was conducted on the same days.
Results: On day 10, ScVO2 was considerably lower than on day 4 (p=0.002). Day 10 had a considerably increased oxygen delivery (DO2) than Day 4 (p=0.025). Day 10 had a considerably lower Index of Contractility (ICON) than Day 4 (p=0.014).
Conclusions: Preterm newborns showed improved tissue oxygenation after a successful transition that could predict a good outcome.

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